The relationship in between infection and conventional antibiotics

Could CBD work in the battle versus resistant bacterial pressures? The arise from the University of Queensland in Australia recommend that it is possible. However before taking a look at the study in depth, it is useful to comprehend the development of the relationship in between bacteria and antibiotics.

Considering that the advanced discovery of penicillin by Alexander Fleming in 1928, antibiotics have been a vital tool in the battle versus bacteria and infections. And although we still use the same tested methods today, bacteria have evolved. When exposed to antibiotics, particular bacteria, fungis and parasites have the ability to adjust and cancel the efficiency of the drug by developing resistance.

It’s worth mentioning that antimicrobial resistance was likely to occur anyway, as the genetic code for bacteria modifications with time. However, it is believed that the overuse of antibiotics is a crucial aspect that accelerates the development of resistant pressures.

According to the World Health Organization, antimicrobial resistance “is an increasingly serious danger to worldwide public health that needs action in all sectors of federal government and in society.” This has actually led researchers to think outside the box by trying to identify substances that could be beneficial in the battle versus harmful bacteria. Among these substances is cannabidiol (CBD), a cannabinoid found in Cannabis sativa.

Researchers are searching for new methods to attack infections and resistant bacteria.

Dr. Mark Blaskovich, Principal Investigator and Program Coordinator for the Community for Open Antimicrobial Drug Discovery and Senior Research Officer at the Institute for Molecular Bioscience at the University of Queensland, concluded that CBD works versus Gram-positive bacteria. Stress of Gram-positive bacteria consist of Staphylococcus aureus (common in skin infections) and Streptococcus pneumoniae (common in bacterial pneumonia).

Dr. Blaskovich provided his findings at a yearly meeting of the American Society for Microbiology. In vitro samples of both types of gram-positive bacteria were treated with artificial CBD. The results led Dr. Blaskovich to the conclusion that CBD works at levels similar to those of prescription antibiotics vancomycin and daptomycin. He also discovered that CBD appeared to work against gram-positive pressures of resistant bacteria, which many conventional antibiotics are beginning to fail.

” In particular, the activity was chosen versus the resistant pressures of Staphylococcus aureus (MRSA, VISA, SARV), Streptococcus pneumoniae (MDR), and Enterococcus faecalis (ERV). Cannabidiol was bactericidal, had a low tendency to cause resistance and was active versus MRSA biofilms. “

The group also conducted another study using topical CBD to treat a skin infection in mice. Once again, although the results were positive, CBD did not appear to get rid of the infection, but merely to minimize the number of bacterial cells.

Could CBD end up being an antibiotic?

While it is easy to hail this work as a substantial advancement in the antibacterial capabilities of CBD, it is too soon to quit on penicillin.

Although it is believed that the efficiency of CBD could originate from the method it assaults the biofilm surrounding bacterial cells, the authors are still unsure of the mechanism of action of new earth CBD. They also did not be reluctant to mention the drawbacks of the study. Dr. Blaskovich pointed out that because the results remain in the initial stages, it is far prematurely for individuals to begin treating their CBD infections themselves.

The study was also conducted in vitro (outside the human body), and there is a risk that the results of medical trials will not be the same. Numerous substances have shown antibacterial efficacy in petri dishes, but then stopped working at this crucial phase. It needs to also be pointed out that the two studies were performed in cooperation with Botanix Pharmaceuticals Ltd, a pharmaceutical company focusing on topical CBD Cities products.

However, this research study could be a crucial advance for CBD and the battle versus antimicrobial resistance. CBD continues to have a great safety profile and is ruled out toxic even in large amounts. Luckily, Dr. Blaskovich and his group strategy to continue their research study.

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